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Testosterone is metabolized to DHT by the enzyme 5 alpha-reductase. The autosomal recessive genetic disorder of 5 alpha-reductase deficiency has clearly .

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The enzyme 5-alpha reductase is present in small amounts in muscle and converts testosterone to dihydrotestosterone (DHT). Testosterone affects lean body.

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5α-reductases, also known as 3-oxo-5α-steroid 4-dehydrogenases, are enzymes involved in Beyond reducing testosterone to dihydrotestosterone, 5alpha- reductase enzyme isoforms I and II reduce progesterone to dihydroprogesterone .

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Jaime A. Cavallo, Steven A. Kaplan, in Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia, 5-Alpha Reductase Enzyme Family. The 5- alpha.

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As with most single enzyme disorders, 5-alpha-reductase type 2 deficiency is autosomal recessive and sex limited because it only causes a.

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Despite the discovery of 5 alpha-reduction as an enzymatic step in steroid metabolism in , and the discovery that dihydrotestosterone is.

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What is 5a-Reductase? 5a-Reductase 5α-reductase Enzyme. 5 alpha-reductase (also known as 5aR) is a special type of enzyme that helps the.

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Dutasteride is a 5 alpha reductase enzyme inhibitor used in men who have a condition known as benign prostatic hyperplasia (BPH).